Blinken addressed reporters at the State Department ahead of meetings of U.S. and Russian diplomats in Europe next week aimed at bringing down the temperature between Russia and the West, and after a virtual meeting with NATO foreign ministers earlier on Friday.
Blinken said Russia has worked for years to undermine Ukraine's democratic institutions, interfere in its politics, block energy and commerce and sow mistrust with propaganda and disinformation.
Russia had positioned nearly 100,000 troops near its border with Ukraine "with plans to mobilize twice that number on very short order" and justified doing so with "misinformation" that Ukraine was seeking to provoke a conflict, Blinken said.
"That's like the fox saying it had to attack the hen house because its occupants somehow pose a threat. We've seen this gaslighting before," Blinken said, citing Russia's 2014 seizure of Crimea and backing of separatists in the Donbass region.
"The idea that Ukraine is the aggressor in this situation is absurd," Blinken said, adding that Moscow was "simultaneously driving the false narrative that NATO is threatening Russia."
But a diplomatic solution was still possible and preferable, and there were areas of potential progress in next week's meetings, Blinken said.
"Next week we’ll reconfirm our readiness to increase transparency, institute new risk-reduction measures and renew efforts to address nuclear and conventional threats to European security," he said. "But again, it has to be a two-way street.”