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Wednesday, Feb 26, 2025

US Reports Human Cases of H5N1 Bird Flu Amid Rising Seasonal Flu Outbreak

US Reports Human Cases of H5N1 Bird Flu Amid Rising Seasonal Flu Outbreak

Two individuals hospitalized with H5N1 bird flu highlight concerns over potential reassortment with seasonal influenza.
Two individuals in the United States have been hospitalized due to H5N1 avian influenza, as reported in a routine update by the Centers for Disease Control and Prevention (CDC).

One patient is from Wyoming and is currently hospitalized, while the other, from Ohio, has been discharged and is recuperating at home.

Both individuals exhibited respiratory symptoms as well as other unspecified complications.

The case in Wyoming involves an older woman who had been exposed to infected poultry in a backyard flock.

Health officials noted that she has preexisting health conditions that may make her more vulnerable to severe illness.

In contrast, the Ohio patient contracted the virus while depopulating infected poultry at a commercial facility.

As of this report, 70 confirmed cases of the highly pathogenic H5N1 strain have been recorded in the U.S. since its detection in livestock last year.

There is currently no evidence of human-to-human transmission of the virus.

Most cases have involved individuals with close contact with infected birds or poultry.

The emergence of these human cases occurs during one of the most severe seasonal flu outbreaks in the past 15 years, raising concerns among public health experts about the potential for reassortment—a process where different strains of viruses exchange genetic information, possibly leading to more virulent forms of the virus.

Angela Rasmussen, a virologist at the Vaccine and Infectious Disease Organization, expressed concern that the hospitalization of H5N1 cases within hospitals treating seasonal flu patients could facilitate reassortment.

Previous notable cases include a Missouri patient who was hospitalized without known exposure and a fatality in Louisiana, which also involved exposure to backyard birds.

A particularly severe case involved a 13-year-old girl in British Columbia who experienced lengthy hospitalization despite no known exposure.

Recent shifts in poultry management strategies are being considered by the federal administration, with potential changes regarding how avian influenza outbreaks are managed.

The incumbent head of health agencies has reportedly halted a seasonal flu vaccination campaign.

In related research regarding influenza, studies published in the CDC’s Emerging Infectious Diseases journal suggest that prior infection with seasonal H1N1 may provide some degree of cross-protection against H5N1.

In experiments involving ferrets, animals with recent H1N1 antibodies demonstrated a quicker neutralization response to H5N1, implying possible protective effects for humans.

Simultaneously, the World Health Organization has projected a significant increase in breast cancer diagnoses and mortality globally by 2050, emphasizing the need for enhanced public health initiatives focused on early detection and prevention.

This data was released by the International Agency for Research on Cancer (IARC), highlighting a concerning trend that underscores the interrelation of public health challenges worldwide.
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